{"id":1552,"date":"2021-09-25T13:59:40","date_gmt":"2021-09-25T04:59:40","guid":{"rendered":"https:\/\/ss-center.com\/blog\/?p=1552"},"modified":"2021-09-25T13:59:40","modified_gmt":"2021-09-25T04:59:40","slug":"%e8%91%89%e9%85%b8%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"post","link":"https:\/\/ss-center.com\/blog\/2021\/09\/25\/%e8%91%89%e9%85%b8%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/","title":{"rendered":"\u8449\u9178\u306b\u3064\u3044\u3066"},"content":{"rendered":"
\u4eca\u56de\u306f\u8449\u9178\u306b\u3064\u3044\u3066\u66f8\u304d\u307e\u3059\u3002<\/span><\/div>\n
\u00a0<\/span><\/div>\n
\u8449\u9178\u306b\u306f\u5929\u7136\u8449\u9178\u5869\u3068\u4eba\u5de5\u8449\u9178\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/div>\n
\u00a0<\/span><\/div>\n
\u65e5\u672c\u3067\u6d41\u901a\u3057\u3066\u3044\u308b\u8449\u9178\u306e\u307b\u3068\u3093\u3069\u304c\u4eba\u5de5\u8449\u9178\u3067\u3059\u304c\u30fb\u30fb\u30fb<\/span><\/div>\n
\u00a0<\/span><\/div>\n
\u5929\u7136\u8449\u9178\u5869\uff08Folate\uff09
\n\u4eba\u5de5\u8449\u9178\uff08FolicAcid\uff09<\/u><\/b><\/span><\/div>\n

\n\u5929\u7136\u8449\u9178\u5869\u3068\u4eba\u5de5\u8449\u9178\u3067\u306f\u4f53\u5185\u3067\u65b0\u9673\u4ee3\u8b1d\u306e\u3055\u308c\u65b9\u304c\u4e21\u8005\u306e\u9593\u3067\u306f\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/span><\/div>\n

\n\u5929\u7136\u306e\u8449\u9178\u5869\u306f\u5c0f\u8178\u5185\u3067\u4ee3\u8b1d\u3055\u308c\u308b\u3068\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\u5869(THF)\u306b\u5909\u63db\u3055\u308c\u30e1\u30c1\u30eb\u5316\u3057\u307e\u3059\u3002<\/span><\/div>\n

\n\u4eba\u5de5\u8449\u9178\u306f\u3053\u308c\u3068\u306f\u7570\u306a\u308a\u3001\u6700\u521d\u306b\u809d\u81d3\u306e\u4e2d\u3067\u9084\u5143\u3055\u308c\u30e1\u30c1\u30eb\u5316\u3055\u308c\u3001\u3053\u3053\u3067\u306f\u8449\u9178\u3092\u8eab\u4f53\u304c\u5229\u7528\u3067\u304d\u308b\u6d3b\u6027\u5316HF\u5f62\u614b\u306b\u5909\u63db\u3059\u308b\u305f\u3081\u306b\u9175\u7d20\u30b8\u30d2\u30c9\u30ed\u8449\u9178\u5869(DHF)\u9084\u5143\u9175\u7d20\u304c\u5fc5\u9808\u3067\u3059(THF\u306f\u8840\u6db2\u8133\u95a2\u9580\u3055\u3048\u901a\u904e\u3059\u308b\u306e\u3067\u3001\u8449\u9178\u5869\u304c\u795e\u7d4c\u969c\u5bb3\u306b\u5bfe\u3057\u3066\u52b9\u304f\u3053\u3068\u3092\u8aac\u660e\u3067\u304d\u308b\u4e00\u3064\u306e\u8981\u56e0\uff09\u3002<\/span><\/div>\n

\n\u300cFolic Acid(\u4eba\u5de5\u8449\u9178)\u300d\u306f\u3001\u5438\u53ce\u7387\u306f\u9ad8\u3044\u306e\u3067\u3059\u304c\u751f\u7406\u6d3b\u6027\u306e\u9ad8\u3044\u300c\u30e1\u30c1\u30eb\u8449\u9178\u5869\u300d\u306b\u5909\u63db\u3055\u308c\u306a\u3044\u3068\u4f53\u5185\u3067\u5229\u7528\u3055\u308c\u307e\u305b\u3093\u3002<\/span><\/div>\n

\n\u3068\u3053\u308d\u304c\u5909\u63db\u3059\u308b\u907a\u4f1d\u5b50\u306b\u7570\u5e38\u304c\u3042\u3063\u3066\u3001\u300cFolic Acid(\u4eba\u5de5\u8449\u9178)\u300d\u3092\u300c\u30e1\u30c1\u30eb\u8449\u9178\u5869\u300d\u306b\u5909\u63db\u3067\u304d\u306a\u3044\u907a\u4f1d\u5b50\u7570\u5e38\u306e\u4eba\u304c\u3044\u307e\u3059\u3002
\n\u305d\u308c\u306f\u3001\u65e5\u672c\u4eba\u306e40\uff5e50\uff05\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/span><\/b><\/u><\/span><\/span>\u8449\u9178\u306e\u4ee3\u8b1d\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\u306f
\nMTHFR\u907a\u4f1d\u5b50\u306eC677T\uff06A1298C\u306e2\u7a2e\u985e\u3067\u3059\u3002<\/span><\/u><\/b><\/p>\n

\u91cd\u8981\uff01
\n<\/u><\/b>\u65e5\u672c\u4eba\u306e40\uff05\uff5e50\uff05\u306fMTHFR\u907a\u4f1d\u5b50\u306eC677T\u3068A1298C\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308a\u307e\u3059\u306e\u3067Folic Acid(\u4eba\u5de5\u8449\u9178)\u3067\u306f\uff12\u4eba\u306b\uff11\u4eba\u6d41\u7523\u3084\u4e0d\u598a\u3001\u795e\u7d4c\u7ba1\u6b20\u640d\u306e\u30ea\u30b9\u30af\u3092\u6539\u5584\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/b><\/u><\/p>\n<\/div>\n

\u00a0<\/span><\/div>\n
\u3055\u3089\u306b\u5929\u7136\u8449\u9178\u306b\u3082\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/div>\n
\u00a0<\/span><\/div>\n
\u300e\u5929\u7136\u8449\u9178\u306e\u7a2e\u985e\u300f<\/span><\/b><\/div>\n
\u00a0<\/span><\/div>\n

\u751f\u7269\u5b66\u7684\u306b\u6d3b\u6027\u5316\u3055\u308c\u305f\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8<\/u><\/b><\/span><\/p>\n


\n\u30fbL-<\/span><\/u><\/b><\/span>\u00a0\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u00a0\u00a0
\n\u30fb6(S)<\/span>\u00a0\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u00a0\u00a0
\n\u30fbL-5-<\/span>\u00a0\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u00a0\u00a0<\/span><\/u><\/b>
\n\u30fbMetafolin\uff08\u30e1\u30bf\u30d5\u30a9\u30ea\u30f3\uff09
\n\u30fbL-Methylfolate Calcium\uff08L-\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u30ab\u30eb\u30b7\u30a6\u30e0\/L-\u30e1\u30c1\u30eb\u8449\u9178\u30ab\u30eb\u30b7\u30a6\u30e0\u5869\uff09
\n\u30fbLevomefolic Acid\uff08\u30eb\u30dc\u30e1\u30d5\u30a9\u30ea\u30c3\u30af\u9178\uff09
\n\u30fbQuatrefolic\uff08\u30af\u30a2\u30c8\u30ec\u30d5\u30a9\u30ea\u30c3\u30af\uff09<\/span><\/u><\/b>
\n<\/span><\/div>\n

\n\u6d3b\u6027\u5316\u3055\u308c\u3066\u3044\u306a\u3044\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8<\/u><\/b><\/span><\/div>\n

\n\u30fbD-<\/span><\/b><\/u><\/span>\u00a0\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u00a0\u00a0
\n\u30fb6(R)<\/span>\u00a0\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u00a0\u00a0
\n\u30fb5-MTHF<\/span><\/span><\/b><\/u><\/div>\n

\n\u6d3b\u6027\u5316\u3055\u308c\u305f\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u3068\u306f\u5224\u65ad\u304c\u4ed8\u304b\u306a\u3044\u30bf\u30a4\u30d7<\/u><\/b><\/span><\/div>\n

\n\u30fbL\u30016(S)\u3001Metafolin\u3068\u660e\u8a18\u3055\u308c\u3066\u3044\u306a\u3044\u3082\u306e
\n\u30fb5-MTHF
\n\u30fb5-methylfolate
\n\u30fb5-methyltetrahydrofolate<\/span><\/u><\/b><\/span><\/p>\n
\u00a0<\/span><\/div>\n

L-\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u3001\u307e\u305f\u306f\u30016(S)-5-\u30e1\u30c1\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\uff086(S)-5-MTHF\uff09\u306f\u6d3b\u6027\u578b\u306e\u30b8\u30a2\u30b9\u30c6\u30ec\u30aa\u7570\u6027\u4f53\u30d5\u30a9\u30ec\u30fc\u30c8\uff08\u8449\u9178\u5869\uff09\u3067\u3042\u308a\u3001\u3053\u308c\u306f\u8449\u9178\u5869\u4ee3\u8b1d\u306b\u304a\u3051\u308b\u57fa\u672c\u7684\u5f62\u614b\u3060\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

\u3053\u306e\u57fa\u672c\u7684\u5f62\u614b\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u8449\u9178\u5869\u306f\u7d30\u80de\u819c\u304b\u3089\u672b\u68a2\u7d44\u7e54\u3078\u3068\u4fb5\u5165\u3057\u3001\u8840\u6db2\u8133\u95a2\u9580\u3082\u7a81\u7834\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u3059\u3002<\/p>\n

\u7d30\u80de\u5185\u30676(S)-5-\u30e1\u30c1\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\uff086(S)-5-MTHF\uff09\u306f\u3001\u30db\u30e2\u30b7\u30b9\u30c6\u30a4\u30f3\u304b\u3089\u30e1\u30c1\u30aa\u30cb\u30f3\u3001\u305d\u3057\u3066\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\u5869\uff08THF\uff09\u3092\u518d\u5408\u6210\u3059\u308b\u30e1\u30c1\u30eb\u5316\u306e\u904e\u7a0b\u3067\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\u5869\uff08THF\uff09\u306f\u3001 \u30c1\u30df\u30b8\u30f3DNA\u3001DNA\u3068RNA\u306e\u30d7\u30ea\u30f3\u57fa\u3001\u305d\u3057\u3066\u3001\u30e1\u30c1\u30aa\u30cb\u30f3\u5408\u6210\u306b\u5fc5\u8981\u306a\u4e00\u70ad\u7d20\u5358\u4f4d\uff08C1 unit:1\u3064\u306e\u70ad\u7d20\u3092\u6709\u3059\u308b\u6b8b\u57fa\u306e\u547c\u79f0\uff09\u306b\u5bfe\u3059\u308b\u76f4\u63a5\u53d7\u5bb9\u4f53\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u98df\u4e8b\u304b\u3089\u6442\u53d6\u3059\u308b\u8449\u9178\u5869\u306e\u7d0470%\u3068\u7d30\u80de\u5185\u306b\u3042\u308b\u8449\u9178\u5869\u306f6(S)-5-\u30e1\u30c1\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\uff086(S)-5-MTHF\uff09\u304b\u3089\u6210\u308a\u307e\u3059\u3002<\/p>\n

\u8449\u9178\u5869\uff08folate\uff09\u306e\u5408\u6210\u578b\u3067\u3042\u308b\u8449\u9178\u304c\u751f\u5316\u5b66\u7684\u306b\u4f7f\u3048\u308b\u6d3b\u6027\u578b\u3078\u3068\u5909\u5f62\u3059\u308b\u306b\u306f\u3001\u30e1\u30c1\u30ec\u30f3\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\u9084\u5143\u9175\u7d20\uff08\uff1d\u30e1\u30c1\u30ec\u30f3\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\u30ec\u30c0\u30af\u30bf\u30fc\u30bc\uff1dMTHFR\uff09\u306b\u3088\u308b\u9175\u7d20\u9084\u5143\u3092\u53d7\u3051\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u30a2\u30b8\u30a2\u570f\u306e\u4eba\u7a2e\uff08\u65e5\u672c\u4eba\uff09\u306e\uff12\u4eba\u306b\uff11\u4eba\u306fMTHFR\u306e\u907a\u4f1d\u5b50\u5909\u7570\uff08\uff23\uff16\uff17\uff17\uff34\uff34\u3001\uff21\uff11\uff12\uff19\uff18\uff34T\uff09\u3092\u6301\u3061\u3001\u8449\u9178\u30926(S)-5-\u30e1\u30c1\u30eb\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\uff086(S)-5-MTHF\uff09\u306b\u4ee3\u8b1d\u5909\u63db\u3055\u305b\u308b\u306e\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3046\u7d30\u80de\u6a5f\u80fd\u306b\u652f\u969c\u3092\u6765\u3059\u539f\u56e0\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/u><\/b><\/p>\n<\/div>\n

\u00a0<\/span><\/div>\n
\n

\u65e5\u672c\u4eba\u306f\u4eba\u5de5\u8449\u9178(Folic Acid)\u3067\u306f\u306a\u304f\u3001\u5929\u7136\u8449\u9178\u5869(Folate)\u306e\u307b\u3046\u3092\u6442\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/span><\/u><\/b><\/span><\/p>\n

\u5929\u7136\u8449\u9178\u5869\uff08Folate\uff09\u3092\u542b\u3080\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u6c42\u3081\u308b\u969b\u306f\u3001\u3088\u304f\u6ce8\u610f\u3057\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u751f\u4f53\u6d3b\u6027\u5f62\u614b\u306e\u3053\u306e\u7269\u8cea\u306f\u975e\u6d3b\u6027\u578b\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u3068\u533a\u5225\u304c\u3064\u304d\u306b\u304f\u3044\u540d\u79f0\u3067\u547c\u3070\u308c\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n

\u5929\u7136\u8449\u9178\u5869\uff08Folate\uff09\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u6c42\u3081\u308b\u3068\u304d\u306f\u3001\u4e0a\u8a18\u306b\u3068\u308a\u308f\u3051\u6ce8\u610f\u3057\u751f\u4f53\u6d3b\u6027\u306e\u3042\u308b\u5929\u7136\u8449\u9178\u5869\u3092\u9078\u3076\u4e8b\u304c\u5927\u5207\u3067\u3059\u3002<\/span><\/u><\/b><\/p>\n<\/div>\n

\u00a0<\/span><\/div>\n
\u598a\u5a20\u3092\u5e0c\u671b\u3059\u308b\u5973\u6027\u3000\u598a\u5a20\u4e2d\u306e\u5973\u6027\u306e
\n\u539a\u751f\u52b4\u50cd\u7701\u63a8\u5968\u91cf\u3000\u8449\u9178\u3000\uff11\u65e5\/480\u03bcg<\/span><\/u><\/b>\u73fe\u5728\u306e\uff13\uff10\u4ee3\u304b\u3089\uff14\uff10\u4ee3\u306e\u65e5\u672c\u4eba\u5973\u6027\u306e1\u65e5\u306b\u98df\u4e8b\u304b\u3089\u6442\u53d6\u3055\u308c\u308b\u98df\u4e8b\u6027\u8449\u9178\uff08\u5929\u7136\u8449\u9178\u5869\uff09\u306f\u5e73\u5747\uff11\u65e5\uff12\uff18\uff10\u03bcg\u3067\u3059\u3002<\/span><\/p>\n

\u539a\u751f\u52b4\u50cd\u7701\u8449\u91781\u65e5\u63a8\u5968\u6442\u53d6\u91cf\u306f\uff14\uff18\uff10\u03bcg\u3067\u3059\u306e\u3067\u3042\u3068\uff12\uff10\uff10\u03bcg\u8db3\u308a\u307e\u305b\u3093\u3002<\/span><\/p>\n

\u68d7\u53c2\u5b9d\u306b\u306f<\/span><\/u><\/b>
\n
\n<\/span><\/p>\n<\/div>\n

\n

\u5929\u7136\u306e\u9ed2\u68d7\u304b\u3089\u62bd\u51fa\u3057\u305f\u751f\u4f53\u6d3b\u6027\u578b\u306e\u5929\u7136\u8449\u9178\u5869\u3010\uff16\uff08S\uff09\u30e1\u30c1\u30eb\u30d5\u30a9\u30ec\u30fc\u30c8\u3011<\/span><\/b>\u3092\uff11\u30ab\u30d7\u30bb\u30eb\u5f53\u305f\u308a\uff13\uff18\uff0e\uff19\u03bcg\u914d\u5408<\/span><\/u><\/b>\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\n

\u598a\u5a20\u3092\u5e0c\u671b\u3059\u308b\u5973\u6027\u3001\u598a\u5a20\u4e2d\u306e\u5973\u6027\u306f<\/span><\/p>\n

\u68d7\u53c2\u5b9d\uff11\u65e5\uff16\u30ab\u30d7\u30bb\u30eb\uff08\uff16\u00d7\uff13\uff18\uff0e\uff19\u03bcg\uff09\uff1d\uff12\uff13\uff13\uff0e\uff14\u03bcg<\/span>
\n\u3092\u6442\u53d6\u3059\u308b\u4e8b\u306b\u3088\u308a<\/span><\/span><\/u><\/b><\/p>\n

\u98df\u4e8b\u6027\u8449\u9178\u5e73\u5747\uff11\u65e5\uff12\uff18\uff10\u03bcg
\n\uff0b
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