{"id":1195,"date":"2019-12-07T11:28:22","date_gmt":"2019-12-07T02:28:22","guid":{"rendered":"http:\/\/ss-center.com\/blog\/?p=1195"},"modified":"2019-12-07T11:28:22","modified_gmt":"2019-12-07T02:28:22","slug":"%e6%9c%80%e8%bf%91%e3%80%81%e7%94%b7%e6%80%a7%e3%81%ae%e6%9d%be%e5%ba%b7%e6%b3%89%e6%9c%8d%e7%94%a8%e5%a2%97%e5%8a%a0%e4%b8%ad%e3%81%a7%e3%81%99%e3%80%82","status":"publish","type":"post","link":"https:\/\/ss-center.com\/blog\/2019\/12\/07\/%e6%9c%80%e8%bf%91%e3%80%81%e7%94%b7%e6%80%a7%e3%81%ae%e6%9d%be%e5%ba%b7%e6%b3%89%e6%9c%8d%e7%94%a8%e5%a2%97%e5%8a%a0%e4%b8%ad%e3%81%a7%e3%81%99%e3%80%82\/","title":{"rendered":"\u6700\u8fd1\u3001\u7537\u6027\u306e\u677e\u5eb7\u6cc9\u670d\u7528\u5897\u52a0\u4e2d\u3067\u3059\u3002"},"content":{"rendered":"

\u3053\u3093\u306b\u3061\u306f\u3002<\/p>\n

\u4f53\u5916\u53d7\u7cbe\u3084\u9855\u5fae\u6388\u7cbe\u3092\u53d7\u3051\u3066\u3044\u308b\u30ab\u30c3\u30d7\u30eb\u306b\u3068\u3063\u3066\u3001\u5973\u6027\u306e\u5e74\u9f62\u306b\u95a2\u4fc2\u306a\u304f\u3001\u7537\u6027\u304c40\u6b73\u4ee5\u4e0a\u306b\u306a\u308b\u3068\u5e74\u9f62\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u6cbb\u7642\u6210\u7e3e\u304c\u4f4e\u4e0b\u3059\u308b<\/strong><\/u>\u3068\u3044\u3046\u7814\u7a76\u5831\u544a\u304c\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u306e\u30e2\u30ca\u30b7\u30e5\u5927\u5b66\u304b\u3089\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\nHum Reprod,\u00a0https:\/\/doi.org\/10.1093\/humrep\/dez223<\/a>\u00a0 \u3000\u2190\u8ad6\u6587<\/u><\/p>\n

1992\u5e74\u304b\u30892017\u5e74\u307e\u3067\u5927\u5b66\u75c5\u9662\u3067\u5b9f\u65bd\u3055\u308c\u305f\u4f53\u5916\u53d7\u7cbe\u3084\u9855\u5fae\u6388\u7cbe24,411\u5468\u671f\u304b\u3089\u3001\u7537\u6027\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u7cbe\u6db2\u691c\u67fb\u7d50\u679c\u304c\u6b63\u5e38\u3067\u3001\u5973\u6027\u30d1\u30fc\u30c8\u30ca\u30fc\u304c\u5b50\u5bae\u5185\u819c\u75c7\u3084\u5375\u7ba1\u9589\u585e\u3001PCOS\u3001\u63a1\u5375\u6570\u304c3\u500b\u672a\u6e80\u308415\u500b\u4ee5\u4e0a\u3001\u3055\u3089\u306b\u306f\u3001\u51cd\u7d50\u5375\u5b50\u3001\u51cd\u7d50\u7cbe\u5b50\u3092\u4f7f\u3063\u305f\u6cbb\u7642\u3092\u9664\u3044\u305f\u539f\u56e0\u4e0d\u660e\u4e0d\u598a\u75c7\u30ab\u30c3\u30d7\u30eb\u306e2,425\u5468\u671f\u3092\u5bfe\u8c61\u306b\u6cbb\u7642\u6210\u7e3e\u3078\u306e\u7537\u6027\u3084\u5973\u6027\u306e\u5e74\u9f62\u306e\u5f71\u97ff\u3092\u8abf\u3079\u305f\u7d50\u679c\u3067\u3059\u3002<\/p>\n

\u5973\u6027\u306e\u5e74\u9f62\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u6cbb\u7642\u6210\u7e3e\u304c\u4f4e\u304f\u306a\u308b\u3053\u3068\u306f\u3001\u3088\u304f\u3088\u304f\u3001\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u3068\u306f\u95a2\u4fc2\u306a\u304f\u3001\u307e\u305f\u3001\u5973\u6027\u307b\u3069\u306e\u5f71\u97ff\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u7537\u6027\u308240\u6b73\u4ee5\u964d\u3001\u5e74\u9f62\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u6cbb\u7642\u6210\u7e3e\u306f\u4f4e\u304f\u306a\u308b<\/u><\/strong>\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u7537\u6027\u306e\u5e74\u9f62\u304c1\u6b73\u9ad8\u304f\u306a\u308b\u3054\u3068\u306b\u51fa\u7523\u306b\u81f3\u308b\u78ba\u7387\u306f4.1%\u4f4e\u304f\u306a\u308b<\/u><\/strong>\u3068\u306e\u3053\u3068\u3002<\/p>\n

\u5b9f\u969b\u3001\u3053\u308c\u307e\u3067\u3082\u7537\u6027\u306e\u5e74\u9f62\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u306f\u3044\u304f\u3064\u3082\u306e\u7814\u7a76\u5831\u544a\u304c\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

2112\u540d\u306e\u5973\u6027\u3092\u5bfe\u8c61\u306b\u7537\u6027\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u5e74\u9f62\u3068\u5b50\u3065\u304f\u308a\u3092\u59cb\u3081\u3066\u304b\u3089\u598a\u5a20\u306b\u81f3\u308b\u307e\u3067\u306e\u671f\u9593\u306e\u95a2\u4fc2\u3092\u8abf\u3079\u305f\u30a4\u30ae\u30ea\u30b9\u306e\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u3002
\n
\n<\/u><\/p>\n

Fertil Steril 2003; 79: 1520.\u00a0\u00a0<\/u>\u00a0https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12801554<\/a>\u00a0\u00a0\u00a0 \u3000\u2190\u8ad6\u6587\u00a0<\/u><\/p>\n

\u305d\u308c\u306b\u3088\u308b\u3068\u3001\u7537\u6027\u304c20\u4ee3\u3067\u306f\u7d046\u304b\u6708\u306a\u306e\u304c\u300130\u4ee3\u304b\u308940\u4ee3\u524d\u534a\u306b\u306a\u308b\u3068\u3060\u3068\u3001\u7d0410\u30f6\u6708\u306b\u300140\u4ee3\u5f8c\u534a\u306b\u306a\u308b\u3068\u7d041\u5e74\u534a\u3001\u305d\u3057\u3066\u300150\u6b73\u4ee5\u4e0a\u306b\u306a\u308b\u3068\uff12\u5e74\u534a\u4ee5\u4e0a\u304b\u304b\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u7537\u6027\u306e\u5e74\u9f62\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u5973\u6027\u304c\u598a\u5a20\u3059\u308b\u307e\u3067\u306b\u9577\u304f\u304b\u304b\u308b<\/u><\/strong>\u3088\u3046\u306b\u306a\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u3053\u3067\u3082\u7537\u6027\u304c40\u6b73\u3092\u8d85\u3048\u308b\u9803\u304b\u3089\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u5973\u6027\u304c\u598a\u5a20\u3057\u306b\u304f\u304f\u306a\u308b\u50be\u5411<\/u><\/strong>\u304c\u898b\u3066\u53d6\u308c\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u7537\u6027\u306e\u5e74\u9f62\u306f\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u6d41\u7523\u7387\u3082\u4e0a\u6607\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u30025121\u540d\u306e\u5973\u6027\u3092\u5bfe\u8c61\u306b\u7537\u6027\u30d1\u30fc\u30c8\u30ca\u30fc\u3068\u6d41\u7523\u7387\u306e\u95a2\u4fc2\u3092\u8abf\u3079\u305f\u30a2\u30e1\u30ea\u30ab\u306e\u7814\u7a76\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

Am J Epidemiol.\u00a02005; 161: 816.\u00a0 \u3000<\/u>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15840611<\/a>\u3000\u2190\u8ad6\u6587\u00a0 \u00a0<\/u>
\n\u305d\u308c\u306b\u3088\u308b\u3068\u3001\u7537\u6027\u306e\u5e74\u9f62\u304c20\u6b73\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u5973\u6027\u306e\u6d41\u7523\u7387\u3092\uff11\u3068\u3057\u305f\u5834\u5408\u300135\u6b73\u30671.43\u300140\u6b73\u306b\u306a\u308b\u30681.58\u300145\u6b73\u30671.74\u3001\u305d\u3057\u3066\u300150\u6b73\u3067\u306f1.90\u500d\u3068\u3001\u7537\u6027\u306e\u5e74\u9f62\u304c\u9ad8\u304f\u306a\u308b\u307b\u3069\u5973\u6027\u30d1\u30fc\u30c8\u30ca\u30fc\u306f\u6d41\u7523\u3057\u3084\u3059\u304f\u306a\u308b<\/u><\/strong>\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3044\u305a\u308c\u306e\u7814\u7a76\u3067\u3082\u5973\u6027\u306e\u52a0\u9f62\u306e\u5f71\u97ff\u306f\u7d71\u8a08\u7684\u306b\u6392\u9664\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u3088\u3046\u306b\u3001\u5973\u6027\u306e\u5e74\u9f62\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u306f\u3001\u5e83\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u7236\u89aa\u306b\u306a\u308b\u7537\u6027\u306e\u5e74\u9f62\u3082\u3001\u307e\u305f\u3001\u598a\u5a20\u7387\u3084\u51fa\u7523\u7387\u3001\u6d41\u7523\u7387\u306b\u30de\u30a4\u30ca\u30b9\u306e\u5f71\u97ff\u3092\u53ca\u307c\u3059\u306e\u3067\u3059\u3002<\/u><\/strong><\/p>\n

\u305d\u308c\u306b\u5bfe\u3057\u3066\u73fe\u5b9f\u306f\u3069\u3046\u304b\u3068\u8a00\u3048\u3070\u3001\u7537\u6027\u306f\u5973\u6027\u3068\u9055\u3044\u3001\u5e74\u3092\u3068\u3063\u3066\u3082\u7cbe\u5b50\u304c\u3064\u304f\u308a\u7d9a\u3051\u3089\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u7cbe\u6db2\u691c\u67fb\u3067\u554f\u984c\u304c\u306a\u3051\u308c\u3070\u3001\u554f\u984c\u306a\u3044\u3060\u308d\u3046\u3068\u53d7\u3051\u6b62\u3081\u3089\u308c\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n

 <\/p>\n

\u3068\u3053\u308d\u304c\u3001\u7cbe\u5b50\u306e\u300c\u91cf\u300d\u3067\u306f\u306a\u304f\u300c\u8cea\u300d\u306b\u76ee\u3092\u5411\u3051\u3066\u307f\u308b\u3068\u3001\u7537\u6027\u306e\u5e74\u9f62\u304c\u9ad8\u304f\u306a\u308c\u3070\u306a\u308b\u307b\u3069\u3001\u7cbe\u6db2\u691c\u67fb\u306e\u7d50\u679c\u306b\u304b\u304b\u308f\u3089\u305a\u3001\u7cbe\u5b50\u306e\u8cea\u306e\u6307\u6a19\u3068\u3055\u308c\u3066\u3044\u308b\u7cbe\u5b50\u306eDNA\u306e\u640d\u50b7\u7387\u304c\u9ad8\u304f\u306a\u308b<\/u><\/strong>\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002
\n
\n<\/u><\/p>\n

Fertil Steril 2017; 101: 1588\u00a0\u3000<\/u>https:\/\/www.fertstert.org\/article\/S0015-0282(18)30015-3\/fulltext<\/a>\u3000\u00a0 \u2190\u8ad6\u6587\u00a0 \u00a0<\/u>
\n\u3064\u307e\u308a\u3001\u7537\u6027\u308240\u6b73\u3092\u8d85\u3048\u308b\u3068\u3001\u7cbe\u6db2\u691c\u67fb\u306e\u7d50\u679c\u306b\u95a2\u4fc2\u306a\u304f\u3001\u7cbe\u5b50\u306e\u8cea\u304c\u4f4e\u4e0b\u3057\u3001\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u5973\u6027\u306f\u598a\u5a20\u3057\u3065\u3089\u304f\u306a\u308b<\/strong><\/u>\u306e\u3067\u3059\u3002<\/p>\n

\u305d\u3046\u3067\u3059\u3001\u5e74\u9f62\u304c\u9ad8\u3044\u30ab\u30c3\u30d7\u30eb\u306f\u3001\u5375\u5b50\u306e\u8cea\u3060\u3051\u3067\u306a\u304f\u3001\u7cbe\u5b50\u306e\u8cea\u306b\u3082\u76ee\u3092\u5411\u3051\u308b\u3079\u304d\u306a\u306e\u3067\u3059\u3002<\/p>\n

\u305d\u3057\u3066\u3001\u3053\u3053\u304c\u5927\u4e8b\u306a\u3068\u3053\u308d\u3067\u3059\u304c\u3001\u7cbe\u5b50\u306f\u5e38\u306b\u3064\u304f\u308a\u7d9a\u3051\u3089\u308c\u3066\u3044\u308b\u306e\u3067\u3001\u8cea\u306e\u6539\u5584\u306e\u305f\u3081\u306b\u51fa\u6765\u308b\u3053\u3068\u304c\u3044\u304f\u3064\u304b\u3042\u308b\u306e\u3067\u3059\u3002<\/p>\n

\u305f\u3068\u3048\u3070\u3001\u7981\u6b32\u671f\u9593\u3092\u77ed\u304f\u3059\u308b\u3053\u3068\u3002<\/p>\n

 <\/p>\n

\u983b\u7e41\u306b\u5c04\u7cbe\u3057\u3066\u3044\u308c\u3070\u3001\u7cbe\u6db2\u4e2d\u306b\u65b0\u9bae\u306a\u7cbe\u5b50\u306e\u5272\u5408\u304c\u5897\u3048\u308b\u304b\u3089\u3067\u3059\u3002\u6700\u4f4e\u3067\u3082\u6570\u65e5\u306b1\u56de\u3001\u51fa\u6765\u308c\u3070\u9694\u65e5\u304b\u3001\u6bce\u65e5\u304c\u7406\u60f3\u3067\u3059\u3002<\/u><\/strong>
\n
\n<\/u><\/p>\n

Fertil Steril 2011;96: 1083.\u00a0\u00a0<\/u>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21924714<\/a>\u3000\u2190\u8ad6\u6587\u00a0\u00a0<\/u>
\n\u307e\u305f\u3001\u5ea7\u308a\u3063\u3071\u306a\u3057\u3092\u907f\u3051\u308b\u3053\u3068\u3002<\/p>\n

 <\/p>\n

\u30c7\u30b9\u30af\u30ef\u30fc\u30af\u306e\u6642\u9593\u3068\u7cbe\u6db2\u691c\u67fb\u7d50\u679c\u306f\u95a2\u9023\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u7cbe\u5b50DNA\u65ad\u7247\u5316\u7387\u3068\u6709\u610f\u306a\u95a2\u9023\u304c\u8a8d\u3081\u3089\u305f<\/u><\/strong>\u3068\u3044\u3046\u7814\u7a76\u5831\u544a\u304c\u306a\u3055\u308c\u3066\u307e\u3059\u3002<\/p>\n

Folia Histochem Cytobiol.\u00a02019; 57: 15.\u00a0\u00a0<\/u>https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30869154<\/a>\u3000\u2190\u8ad6\u6587\u00a0\u00a0<\/u>
\n\u305d\u3057\u3066\u3001\u98df\u4e8b\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u5341\u5206\u306a\u30d3\u30bf\u30df\u30f3\u3084\u30df\u30cd\u30e9\u30eb\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3002<\/u><\/strong><\/p>\n

\u98df\u4e8b\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u30d3\u30bf\u30df\u30f3C\u3084\u30d3\u30bf\u30df\u30f3E\u3001\u4e9c\u925b\u306e\u6442\u53d6\u91cf\u304c\u591a\u3044\u7537\u6027\u3068\u5c11\u306a\u3044\u7537\u6027\u306e\u7cbe\u5b50DNA\u306e\u640d\u50b7\u7387\u3092\u6bd4\u3079\u305f\u3068\u3053\u308d44\u6b73\u672a\u6e80\u306e\u7537\u6027\u3067\u306f\u5dee\u306f\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u306e\u306b\u300144\u6b73\u306e\u7537\u6027\u3067\u306f\u305d\u308c\u3089\u306e\u6804\u990a\u7d20\u306e\u6442\u53d6\u91cf\u304c\u5c11\u306a\u3044\u7537\u6027\u306e\u307b\u3046\u304c\u7cbe\u5b50DNA\u640d\u50b7\u7387\u304c\u591a\u3044\u7537\u6027\u306b\u6bd4\u3079\u3066\u9ad8\u304b\u3063\u305f<\/strong><\/u>\u3068\u30a2\u30e1\u30ea\u30ab\u304b\u3089\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

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 <\/p>\n

\u82f1\u30e1\u30f3\u30ba\u30af\u30ea\u30cb\u30c3\u30af\u3067\u3082\u677e\u5eb7\u6cc9<\/u><\/strong>\u306f\u7cbe\u5b50\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3059\u308b\u70ba\u306b\u60a3\u8005\u69d8\u306b\u670d\u7528\u3057\u3066\u9802\u304d\u826f\u3044\u7d50\u679c\u304c\u51fa\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

 <\/p>\n

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<\/h5>\n
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